'Miracle cure' saves breast cancer patient with only months to live

'Miracle cure' saves breast cancer patient with only months to live

The findings come from a study published simultaneously in the New England Journal of Medicine.

Hormone-receptor-positive, axillary node-negative disease -- the type of breast cancer studied here - accounts for half of all the breast cancer cases in the US, and chemotherapy historically has been part of most women's treatment regimen after surgery.

About 70 percent of women with the most common form of early stage breast cancer can be spared the "agony of chemotherapy", United States researchers say.

'Every day, women with certain types of breast cancer face the bad dilemma of whether or not to have the treatment, without hard facts about the benefit for them'.

This ability of cancer to change its genes - a process called immunoediting - had never been described in colon cancer before, and the new understanding could help researchers develop new immunotherapies that target those genetic changes.

Knowing a patient's recurrence risk can spare them from enduring chemotherapy, but also can direct them towards it if they discover that they are at a higher risk, Sparano says.

Of those, 6,711 scored in the intermediate range of 11-25, and were randomly assigned hormone therapy alone or hormone therapy plus chemotherapy.

James Doroshow, director of the division of cancer treatment and diagnosis at the National Cancer Institute, which was the primary sponsor of the study, predicted that the trial would lead to changes in treatment "for a large number of potential patients".

A woman with an aggressive form of breast cancer which defied chemotherapy and spread to other organs, was cured with an experimental treatment that triggered her immune system, researchers said Monday.

One difference: In women 50 or younger, chemo was associated with a lower risk of cancer recurrence, although the rates of overall survival were similar.

According to the study, gene tests on tumor samples were able to safely identify which women could safely forego chemotherapy.

More news: Apple Just Debuted Powerful New Augmented Reality Features

"Now with these genomic tests, we are finding that we have multiple types of breast cancer, perhaps several dozen", said Brawley, "and we are being able to tailor our therapies to the type of breast cancer every woman has".

Alan Melcher, professor of translational immunotherapy at the Institute of Cancer Research in London, who was not involved in the study said: "The work shows that even cancers like breast cancer, which don't have many antigens, are amenable to this sort of treatment".

In recent years, oncologists have warned that women with early-stage breast cancer are possibly being overtreated.

Past experiments revealed that one group of people particular results of the genetic test would benefit from a combination of endocrine therapy and chemotherapy.

Some of those women have already been skipping chemotherapy based on less rigorous research.

For decades, chemotherapy has been seen as a necessary evil when it comes to treating most kinds of breast cancer. Protectively, many of those women have received chemotherapy, which can have devastating side effects, including anemia, a weakened immune system, hair loss, diarrhea, fatigue and memory loss.

According to the TAILORx researchers, 260,000 women who are diagnosed with breast cancer each year around the world fall into the medium-risk category that wouldn't benefit from chemotherapy. The results showed there might be a small benefit from chemotherapy. The patient's cancer could not have spread to the lymph nodes. But then the disease returned with a vengeance and failed to respond to multiple hormonal and chemotherapy treatments.

Still, massive well done to these brilliant doctors, and we hope Judy continues to live a long and happy hike-filled, cancer-free life. Those who score 26 or higher on the scale do benefit and now receive chemotherapy.

Now she's filling her life with backpacking and sea kayaking and has just taken five weeks circumnavigating Florida.

"This is going to provide the highest level of evidence now for our test being indispensable in clinical practice", Shak said.

Related Articles

  • Apple Falls Between The Russian Authorities And Telegram App

    Apple Falls Between The Russian Authorities And Telegram App

    The agency then sent letters to Apple and Google demanding that the app be removed from the App Store and the Google Play Store. It appears that this message had its coveted impact, as Apple has now clearly permitted the main iOS Telegram update in months.
    Novak Djokovic enters Quarter-finals, complains about slippery court

    Novak Djokovic enters Quarter-finals, complains about slippery court

    Khachanov, the 6ft 6in Russian ranked 38 in the world, this time had no answer as Zverev took the match 4-6 7-6 (7/4) 2-6 6-3 6-3. Even though he trails Thiem in their head-to-head, he won their most recent meeting on clay in the Madrid final this year.
    Pentagon Warns Syria Against Attacking Kurdish-led Forces

    Pentagon Warns Syria Against Attacking Kurdish-led Forces

    Al-Moallem said that only when US troops withdraw from the Tanf area near the Jordanian border can an agreement be discussed. USA forces are based in a southern desert pocket further east at Tanf, a strategic highway border crossing with Iraq.
  • IOS 12, macOS, watchOS 5 and more

    IOS 12, macOS, watchOS 5 and more

    Create Animojis That Look Like You. -Apple's next iOS version will offer insights on how you use your iOS device. Also, the Stocks app will come to iPads with iOS 12 . -Apple claims Siri gets 10 billion requests every month.
    Starbucks' Howard Schultz steps down as executive chairman

    Starbucks' Howard Schultz steps down as executive chairman

    In a farewell letter to employees, Schultz noted he had created a personal website , which talks of a "new chapter". Starbucks declined to make Schultz or other Starbucks executives and board members available for comment.
    Use Your Apple Watch as a Walkie Talkie, Coming Later This Year

    Use Your Apple Watch as a Walkie Talkie, Coming Later This Year

    The Apple Watch is all about making simple actions easily accessible with a single tap or putting notifications at a glance. As usual, there are lots of new features that have to do with fitness tracking, and one of those features is Competitions.
  • In secret memo, Trump lawyers talk up presidential powers

    In secret memo, Trump lawyers talk up presidential powers

    Negotiations between Trump's lawyers and the special counsel on a possible interview have continued since. Trump tweeted earlier on Saturday.
    Warriors' Game 2 Win Sees NBA Finals Rise

    Warriors' Game 2 Win Sees NBA Finals Rise

    James scored 51 points in Game 1, making challenging shots few others would even attempt, and it wasn't enough. The Warriors earned a wacky 124-114 overtime win in Game 1 Thursday night - featuring J.R.
    Putin invited N. Korea's Kim for visit Russian Federation  in September

    Putin invited N. Korea's Kim for visit Russian Federation in September

    Russian President Vladimir Putin has invited North Korean leader Kim Jong Un to Russia to attend an upcoming global forum. An official at South Korea's Unification Ministry said the government was watching the North's leadership very closely.
  • Agent insists: Liverpool must agree Fekir fee with Lyon first

    Agent insists: Liverpool must agree Fekir fee with Lyon first

    L'Equipe journalist Bilel Ghazi posted on Twitter that there has been zero progress between Liverpool and Fekir's representatives. Bayern Munich , who bought Corentin Tolisso from Lyon last summer, are believed to be eyeing Fekir up too.
    Apple's software improvements could make AR as universal as iOS

    Apple's software improvements could make AR as universal as iOS

    FaceTime will be able to host 32 video tiles at once, with the tiles expanding and shrinking depending on who's talking. With Measure , you can measure objects or walls around you thanks to some new augmented reality tools from Apple .
    Facebook shared user data with Apple and Samsung

    Facebook shared user data with Apple and Samsung

    The FTC is now investigating Facebook's privacy practices in light of the Cambridge Analytica data misuse scandal . Facebook has had to rethink its relationship to such third-party data providers and developers.